ORIGINAL: CB on the run
How many grains? Still tinkering with my Rem 760 in the .308.
40 grains of H4895 got me to around 2600 fps with the Hornady 165 grain SP. However, if I were starting over again, I would be starting with the 150 grain bullet. It just so happened that my Savage 99 wouldn't group 150's worth spit. I tried 165's as a fallback and they worked.
H4895 works well, because of two things:
1) It gives a consistent velocity in less-than-max loadings.
2) It is very easy on the shoulder.
I originally used Varget instead of H4895, but switched. I made the move several years ago to see if I could get down to a single rifle powder. It made loading my rifles much cheaper to buy one powder in larger quantities. H4895 fuels all my deer rifles now.