A 30.06 is probably one of the most common calibers for rifle hunting. The .243 is probably on the small end of things. I'm not sure that a 22-250 is legal in all state. I have a .308 and love it. I've thought about upgrading to a .300 WSM, but it is more of a wish list. I've always felt that you use the most lethal method available.
Don't know where you hunt..But you did arouse my curiosity on the point..To where i aksed the Gunsmith at the local Gander mountain as well..And he as well stands by the following..
30.06 is way to expensive..Way to much overkill, A moderate kick/loudness, allows everyone in the county to hear where you shot that buck from..And is more for bear-elk, larger game. Keep in mind we both have been hunting for over 30 years.
I've heard great debates about to bait or not to bait. We bait. I think that it is ethical to do so. I don't think it will increase your odds of getting a big buck. They won't come in during daylight. At least not during the rut. The game camera proves that.
1. Big Bucks do come out to play at the daytime:) Its called a pervious full moon..And they do come out during the day during a rut. thats a fact jack:)