I covered an open work territory in Nashville, TN a few years back. I usually stayed in Franklin or Brentwood. The few times I did stay in Nashville proper, I stayed near Vanderbilt. I always had a good time and never had any problems, even in some of the less desirable neighborhoods North of the river. Depending upon how far you are from your work location, the morning and evening commutes can be hectic.
If you get a chance, check out Noshville Restaurant.
"This is the world we are born into -- we should never let that slip away from us. May it never cease to stimulate, inspire and humble us." from Stalking & Still-Hunting: The Ground Hunter's Bible by G. Fred Asbell