Kentucky allows using 45ACP, but I do not know anyone that hunts with it. It it were just up to you and me, I'd say act responsibly and go for it. The problem is that it's not.
I've been in online hunting forums since before there was an Internet. I have seen folks talk about taking deer with everything from 25 Auto up to a civil war cannon. There's a whole school of folks that say .22 LR is the preferable round, because that is what deer control snipers use. Yes, there are those who believe it is a good round for deer. Personally, I would carry the 44 Mag and not worry about it.
The problem is that it opens up a can of worms if you do it and then get online and shout about it. There are arguments over it just being a stunt. There are arguments over whether or not you are a slob. There are arguments over whether or not you are feeding the anti-hunters.
My advice is to use your own conscience, and just don't crow about it afterward.